a3o™ elemental serum
First-of-its-kind, patent-pending antioxidant serum powered by the A3O™ Complex to actively support the skin’s natural collagen production, improve texture, enhance tone and strengthen its overall barrier function.
Combining Acetyl Zingerone, Bakuchiol, and a fatty acid ester, our Patent-pending, triple-pathway anti-senescent molecule helps firm skin, enhances tone, and brightens the complexion with results that rival Vitamin C, without the irritation.*
Developed over years of R&D, including clinical work and published research on individual components by our dermatologist-led medical advisory board, we were very intentional about each ingredient and the optimal method to combine them in our complex. We believe this will reset the industry’s expectations for antioxidant molecules moving forward.
Calm instead of irritate. Stable in sunlight instead of breaking down. Stimulating the skin’s natural Collagen and helping set the stage for aging well*.
Deeply hydrates and plumps for smoother, more elastic-feeling skin*.
Helps to strengthen the skin’s natural moisture barrier to lock in hydration*.
Provides antioxidant protection and helps retain skin moisture*.
Soothes dry, irritated skin and is gentle for sensitive skin*.
inner dose™
daily skin supplement
Designed with a strategic blend of antioxidants, adaptogens, and micronutrients, the dermatologist-formulated capsule addresses internal triggers of aging to preserve skin clarity, strength, and resilience over time*.
280 mgHelps to enhance the skin’s natural internal UV defense and photoprotection—ideal for individuals with daily sun exposure*.
500 mgRebalances the body’s natural inflammatory response to help promote a calmer, more even-toned complexion*.
2500 IUSupports skin barrier integrity and improves overall skin vitality*.
6 mgProvides potent antioxidant protection to help preserve skin elasticity, maintain hydration, and reduce the visible signs of aging*.
250 mg
A powerful adaptogen known to help counter the visible effects of stress on the skin*.
A3O™ ELEMENTAL SERUM REFERENCES
1. Chaudhuri, R.K., Meyer, T., Premi, S. and Brash, D. (2020), Acetyl zingerone: An efficacious multifunctional ingredient for continued protection against ongoing DNA damage in melanocytes after sun exposure ends. Int J Cosmet Sci, 42: 36-45. https://doi.org/10.1111/ics.12582
2. Dhaliwal S, Rybak I, Pourang A, et al. Randomized double-blind vehicle controlled study of the effects of topical acetyl zingerone on photoaging. J Cosmet Dermatol. 2021; 20: 166–173. https://doi.org/10.1111/jocd.13464
3. Meyer, T.A.; Swindell, W.R.; Chaudhuri, R.K. Acetyl Zingerone: A Photostable Multifunctional Skincare Ingredient That Combats Features of Intrinsic and Extrinsic Skin Aging. Antioxidants 2023, 12, 1168. https://doi.org/10.3390/antiox12061168
4. Srivastava, J.; Young, M.M.; Yadav, V.K.; Phadatare, P.R.; Meyer, T.A.; Chaudhuri, R.K.; Premi, S. The Role of Acetyl Zingerone and Its Derivatives in Inhibiting UV-Induced, Incident, and Delayed Cyclobutane Pyrimidine Dimers. Antioxidants 2023, 12, 278. https://doi.org/10.3390/antiox12020278
INNER DOSE™ DAILY SKIN SUPPLEMENT REFERENCES
1. Segars K, McCarver V, Miller RA. Dermatologic Applications of Polypodium leucotomos: A Literature Review. J Clin Aesthet Dermatol. 2021 Feb;14(2):50-60. Epub 2021 Feb 1. PMID: 34221229; PMCID: PMC8211346.
2. Zundell MP, Katz A, Shah M, Burshtein J, Rigel D, Zakria D. The Utility of Oral Polypodium Leucotomos Extract for Dermatologic Diseases: A Systematic Review. J Drugs Dermatol. 2025 Apr 1;24(4):346-351. doi: 10.36849/JDD.8410. PMID: 40196953.
3. Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016 Aug;30(8):1243-64. doi: 10.1002/ptr.5640. Epub 2016 May 23. PMID: 27213821.
4. Mata IRD, Mata SRD, Menezes RCR, Faccioli LS, Bandeira KK, Bosco SMD. Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Crit Rev Food Sci Nutr. 2021;61(20):3421-3435. doi: 10.1080/10408398.2020.1798353. Epub 2020 Jul 27. PMID: 32713186.
5. Chang SW, Lee HC. Vitamin D and health - The missing vitamin in humans. Pediatr Neonatol. 2019 Jun;60(3):237-244. doi: 10.1016/j.pedneo.2019.04.007. Epub 2019 Apr 17. PMID: 31101452.
6. Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. Nutrients. 2018 Apr 22;10(4):522. doi: 10.3390/nu10040522. PMID: 29690549; PMCID: PMC5946307.
7. Ng QX, De Deyn MLZQ, Loke W, Foo NX, Chan HW, Yeo WS. Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies. J Diet Suppl. 2021;18(2):169-182. doi: 10.1080/19390211.2020.1739187. Epub 2020 Mar 23. PMID: 32202443.
8. Lima SGM, Freire MCLC, Oliveira VDS, Solisio C, Converti A, de Lima ÁAN. Astaxanthin Delivery Systems for Skin Application: A Review. Mar Drugs. 2021 Sep 9;19(9):511. doi: 10.3390/md19090511. PMID: 34564173; PMCID: PMC8471810.
9. Hilt B, Langård S, Lund-Larsen PG, Lien JT. Previous asbestos exposure and smoking habits in the county of Telemark, Norway--a cross-sectional population study. Scand J Work Environ Health. 1986 Dec;12(6):561-6. doi: 10.5271/sjweh.2106. PMID: 3493526.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
