a3o™ elemental night cream
A transformative, next-generation retinoid with no prescription needed.
Combining Acetyl Zingerone, Bakuchiol, and a fatty acid ester, our Patent-pending, triple-pathway anti-senescent molecule helps firm skin, enhances tone, and brightens the complexion with results that rival Vitamin C, without the irritation.*
Developed over years of R&D, including clinical work and published research on individual components by our dermatologist-led medical advisory board, we were very intentional about each ingredient and the optimal method to combine them in our complex. We believe this will reset the industry’s expectations for antioxidant molecules moving forward.
Calm instead of irritate. Stable in sunlight instead of breaking down. Stimulating the skin’s natural Collagen and helping set the stage for aging well*.
A selective, retinoid derivative that helps improve the appearance of skin texture while being suitable for sensitive skin*.
An antioxidant that helps protect skin from environmental stressors while supporting the skin’s moisture barrier and soothes dry, irritated skin*.
A potent peptide that helps protect the skin from the visible signs of aging, supports firmer feeling skin, and brightens dull-looking skin*.
inner dose™
daily skin supplement
Designed with a strategic blend of antioxidants, adaptogens, and micronutrients, the dermatologist-formulated capsule addresses internal triggers of aging to preserve skin clarity, strength, and resilience over time*.
280 mgHelps to enhance the skin’s natural internal UV defense and photoprotection—ideal for individuals with daily sun exposure*.
500 mgRebalances the body’s natural inflammatory response to help promote a calmer, more even-toned complexion*.
2500 IUSupports skin barrier integrity and improves overall skin vitality*.
6 mgProvides potent antioxidant protection to help preserve skin elasticity, maintain hydration, and reduce the visible signs of aging*.
250 mg
A powerful adaptogen known to help counter the visible effects of stress on the skin*.
A3O™ ELEMENTAL NIGHT CREAM FULL INGREDIENT LIST
FULL INGREDIENT LIST
WATER, CAPRYLIC/CAPRIC TRIGLYCERIDE, GLYCERIN, PENTAERYTHRITYL TETRAETHYLHEXANOATE, EUPHORBIA CERIFERA (CANDELILLA) WAX, ANNONA CHERIMOLA FRUIT EXTRACT, JOJOBA ESTERS, ISOAMYL LAURATE, DIMETHICONE, HYDROGENATED ETHYLHEXYL OLIVATE, ETHYL LINOLEATE, BUTYROSPERMUM PARKII (SHEA) BUTTER, CETEARYL ALCOHOL, HELIANTHUS ANNUUS SEED WAX, CETYL ALCOHOL, ACACIA DECURRENS FLOWER WAX, BAKUCHIOL, CARNOSINE, CITRIC ACID, ECTOIN, ETHYL LINOLENATE, ETHYL OLEATE, ETHYL PALMITATE, GLYCERYL STEARATE, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, HYDROGENATED LECITHIN, PHENOXYETHANOL, PHENYLPROPANOL, PHYTOSTEROLS, POLYGLYCERIN-3, POTASSIUM SORBATE, RICINUS COMMUNIS (CASTOR) SEED OIL, SODIUM ACRYLOYLDIMETHYL TAURATE/VP CROSSPOLYMER, SODIUM BENZOATE, SODIUM CITRATE, SODIUM DEHYDROACETATE, SODIUM PHYTATE, SODIUM STEAROYL GLUTAMATE, TOCOPHEROL, TOCOPHERYL ACETATE, TRIFAROTENYL CAPRYLATE, TRIISOSTEARYL CITRATE, XANTHAN GUM.
REFERENCES
1. Segars K, McCarver V, Miller RA. Dermatologic Applications of Polypodium leucotomos: A Literature Review. J Clin Aesthet Dermatol. 2021 Feb;14(2):50-60. Epub 2021 Feb 1. PMID: 34221229; PMCID: PMC8211346.
2. Zundell MP, Katz A, Shah M, Burshtein J, Rigel D, Zakria D. The Utility of Oral Polypodium Leucotomos Extract for Dermatologic Diseases: A Systematic Review. J Drugs Dermatol. 2025 Apr 1;24(4):346-351. doi: 10.36849/JDD.8410. PMID: 40196953.
3. Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016 Aug;30(8):1243-64. doi: 10.1002/ptr.5640. Epub 2016 May 23. PMID: 27213821.
4. Mata IRD, Mata SRD, Menezes RCR, Faccioli LS, Bandeira KK, Bosco SMD. Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Crit Rev Food Sci Nutr. 2021;61(20):3421-3435. doi: 10.1080/10408398.2020.1798353. Epub 2020 Jul 27. PMID: 32713186.
5. Chang SW, Lee HC. Vitamin D and health - The missing vitamin in humans. Pediatr Neonatol. 2019 Jun;60(3):237-244. doi: 10.1016/j.pedneo.2019.04.007. Epub 2019 Apr 17. PMID: 31101452.
6. Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. Nutrients. 2018 Apr 22;10(4):522. doi: 10.3390/nu10040522. PMID: 29690549; PMCID: PMC5946307.
7. Ng QX, De Deyn MLZQ, Loke W, Foo NX, Chan HW, Yeo WS. Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies. J Diet Suppl. 2021;18(2):169-182. doi: 10.1080/19390211.2020.1739187. Epub 2020 Mar 23. PMID: 32202443.
8. Lima SGM, Freire MCLC, Oliveira VDS, Solisio C, Converti A, de Lima ÁAN. Astaxanthin Delivery Systems for Skin Application: A Review. Mar Drugs. 2021 Sep 9;19(9):511. doi: 10.3390/md19090511. PMID: 34564173; PMCID: PMC8471810.
9. Hilt B, Langård S, Lund-Larsen PG, Lien JT. Previous asbestos exposure and smoking habits in the county of Telemark, Norway--a cross-sectional population study. Scand J Work Environ Health. 1986 Dec;12(6):561-6. doi: 10.5271/sjweh.2106. PMID: 3493526.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.